Dr. Pedro Ramos, Regional Secretary of Health and Civil Protection of Madeira, attended our LTTA in Madeira to inform on the NPS problem and interventions in the autonomous area of Madeira. All so-called “smartshops” selling NPS in Madeira could be closed as early as 2012. Nonetheless, Madeira still has an NPS problem, which is why Dr. Pedro Ramos supports the project to create new techniques for dealing with NPS. Dr. Dirk Kratz (Project Leader) discusses the Erasmus+ project Handle it! – from idea to implementation, and Dr. Thomas Legl talks about euro- TC’s network activity and collaboration with the Handle it!-project.